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Mindfulness and cognitive behavioral therapy improve chronic low back pain

Eight weeks of mindfulness or cognitive behavioral therapy were associated with improved pain, physical function and quality of life and reduced daily opioid dose in adults with chronic low back pain that required treated with daily opioids, according to a new study. This is one of the largest studies to date to evaluate mindfulness and cognitive behavioral therapy as treatment for opioid-treated chronic pain.

Novel genomic screening tool enables precision reverse-engineering of genetic programming in cells

Collaborative research defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation. The method, called ‘Perturb-multiome,’ uses CRISPR to knock out the function of individual transcription factors across many blood cells at once. The researchers then perform single-cell analyses on each cell to measure the effects of the editing, including identifying which genes have been turned on or off and which genes are accessible (based on epigenetic markers).

Drug-delivering aptamers target leukemia stem cells for one-two knockout punch

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report. The aptamers — short single-strand snippets of DNA that can target molecules like larger antibodies do — not only deliver cancer-fighting drugs, but also are themselves toxic to the cancer stem cells, the researchers said.

She Talked Through My Body

My name is Belen and I am from salta, Argentina. About a year ago I went to a very religious place in my city and this is where it all starts. Since I was really young I wanted so bad to talk to spirits and be able to help people I always asked God to give me the opportunity to help people. From my …