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Assembly instructions for enzymes

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they considered the enzymatic reaction of breaking a dimer into two monomer molecules. Considering the geometry of such an enzyme-substrate-complex, they identified three golden rules that should be considered to build a functional enzyme.

A dental floss that can measure stress

Scientists create a floss pick that samples cortisol within saliva as a marker of stress and quantifies it with a built-in electrode. The system uses a polymer casting technology that can be adapted to capture a wide a range of markers, such as estrogen for tracking fertility, or glucose for tracking diabetes. Ease of use allows monitoring to be incorporated into many areas of treatment.

Personal space chemistry suppressed by perfume and body lotion indoors

In 2022 a team discovered that high levels of OH radicals can be generated indoors, simply due to the presence of people and ozone. This means: People generate their own oxidation field and change the indoor air chemistry around them within their own personal space. Now, in a follow-up study again in cooperation with an international research team, they found that commonly applied personal care products substantially suppress a human’s production of OH radicals. These findings have implications for the indoor chemistry, the air quality of occupied spaces, and human health, since many of the chemicals in our immediate vicinity are transformed by this field.